Define "uh-oh moment"

"When you have the secretary of the treasury and the chairman of the Fed say, 'If we don't act boldly, we could be in a depression greater than the Great Depression,' that's an 'uh-oh' moment," [Bush] said. -- Maybe it's just me, but if I was warned of mass unemployment and poverty, my reaction would probably not be the same as when I realize I left my wallet at home. At the very least, I  wouldn't tell everyone my reaction to people losing their jobs was "uh-oh".